Abstract: Duodenal or peptic ulcer is a common problem though the incidence is diminishing now a days, but still it is an important problem and can become life threatening if perforation occurs. Sometimes after perforation the clinical picture in a case of duodenal or gastric perforation resembles acute appendicitis. This problem though produced by peptic ulcer of stomach or duodenum is called Valentino appendix or Valentino’s syndrome. Clinically Valentino appendix mimics acute appendicitis and can confuse the surgeon. A proper history can indicate about peptic ulceration and perforation, but sometimes the appendix is removed as it shows inflammation due to coming in contact of irritant bile containing gastric fluid and contents. Nowadays the laparoscopic procedure can avoid such mishappening.
